AGE - Reader 是第一台採非侵入式判讀組織晚期糖基化終產物 (Advanced Glycation Endproducts, AGEs ) 的儀器。它的主要原理是利用紫外光照射生成之自體螢光反應(skin autofluorescence, skin AF )， 可以快速、即時的預測可能罹患心血管疾病、糖尿病、或腎臟功能不全等疾病的危險機率。
即時、非侵入式、簡單易用、可信準確， 及臨床確認的 AGE - Reader ，可以很方便、有效的偵測晚期糖基化終產物的量， 使得臨床醫師、研究專家， 及製藥公司在開發、處理、監控上， 都可以做最好的掌控。
Relationship between tissue glycation measured by autofluorescence and pulse wave velocity in young and elderly non-diabetic populations. Watta G. et al. Diabetes Metab. 2012 Jun 13.
Advanced glycation end product associated skin autofluorescence: A mirror of vascular function? Hofmann B. et al. Exp Gerontol. 2012 May 12.
Elevated skin autofluorescence is strongly associated with foot ulcers in patients with diabetes: a cross-sectional, observational study of Chinese subjects. Hu H. et al. J Zhejiang Univ Sci B. 2012 May;13(5):372-7.
Advanced Glycation Endproducts and Diabetic Cardiovascular Disease. Prasad A. et al. Cardiol Rev. 2012 Feb 6. Epub
Non-invasive measures of tissue autofluorescence are increased in Type 1 diabetes complications and correlate with a non-invasive measure of vascular dysfunction. Januszewski A.S. et al. Diabet Med. 2011 Dec 28. doi: 10.1111/j.1464-5491.2011.03562.x.
Advanced oxidation protein products and advanced glycation end products in children and adolescents with chronic renal insufficiency. Sebeková K. J Ren Nutr. 2012 Jan;22(1):143-8.
Advanced Glycation Endproducts are increased in RA patients with controlled disease. de Groot L. et al. Arthritis Res Ther. 2011 Dec 14;13(6):R205.
Evaluation of advanced glycation end products accumulation, using skin autofluorescence, in CKD and dialysis patients. Oleniuc M. et al. Int Urol Nephrol. 2011 Dec 10. Epub
Increased skin autofluorescence after colorectal operation reflects surgical stress and postoperative outcome. Pol HW. et al. Am J Surg. 2011 Nov;202(5):583-9.
Skin autofluorescence, as marker of accumulation of advanced glycation endproducts and of cumulative metabolic stress, is not increased in patients with systemic sclerosis. Hettema ME. et al. Int J Rheumatol. 2011. Epub